Controlling Animal Behavior with Light

Yvonne Carts-Powell

Scientists used optogenetics—a combination of genetic engineering and laser technology—to study the pathways between two parts of the brain involved in feeling reward.

Scatterings imageRecent optogenetics research targets the connections between the nucleus accumbens (red) and amygdala fibers (green).

By using low-power laser pulses, researchers at the University of North Carolina at Chapel Hill demonstrated that they could manipulate the brain wiring responsible for reward-seeking behaviors in mice. They used optogenetics—a combination of genetic engineering and laser technology—to study the pathways between two parts of the brain involved in feeling reward, the amygdala and nucleus accumbens (Nature 475, 377, 2011; doi:10.1038/nature10194).

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