Emerging Clinical Applications of Optical Coherence Tomography

Andrew M. Rollins, Michael V. Sivak, Jr., Sunita

Optical coherence tomography (OCT) is an emerging noninvasive imaging technique that provides microscopic tomographic sectioning of biological samples. By measuring backscattered light as a function of depth, OCT fills a valuable niche in imaging of tissue microstructure, providing subsurface imaging with high spatial resolution (on the order of ten micrometers) in three dimensions and high sensitivity in vivo with no contact needed between the probe and the tissue.

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